Modular synthesis of phenanthridine derivatives by oxidative cyclization of 2-isocyanobiphenyls with organoboron reagents.
نویسندگان
چکیده
Where HAS you been? A manganese-mediated annulation of 2-isocyanobiaryls with organoboronic acids is developed for the synthesis of a broad range of phenanthridine derivatives. Mechanistic studies indicate that the reaction proceeds by the intramolecular homolytic aromatic substitution (HAS) of an imidoyl radical intermediate.
منابع مشابه
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عنوان ژورنال:
- Angewandte Chemie
دوره 51 45 شماره
صفحات -
تاریخ انتشار 2012